Cleaved Lamin A 30h5

Product pathways apoptosis phospho lamin a c ser22 antibody 2026 pathway application references companion products datasheet pdf msds pdf protocols have you tried your application using our xp monoclonal antibodies.

Cleaved lamin a 30h5.

The antibody does not cross react with full length lamin a or c. During apoptosis lamin a c is specifically cleaved into a large 41 50 kda and a small 28 kda fragment 3 4. Type b lamins consist of lamin b1 and b2 encoded by separate genes 6 8. Lamin a and c are cleaved by caspases into large 41 50 kda and small 28 kda fragments which can be used as markers for apoptosis 4 5.

Human mouse rat application. Phospho lamin a c ser22 d2b2e xp rabbit mab cell signaling technology. Cleaved lamin a small subunit 30h5 mouse mab cell signaling technology catalog. Product pathways apoptosis cleaved lamin a small subunit 30h5 mouse mab 2036 pathway application references companion products datasheet pdf msds pdf protocols phosphositeplus protein site and accession data.

Lamin b1 is also cleaved by caspases during apoptosis 9. Cleav ed lamin a s mall s ubunit 30h5 mous e ma b det ec t s endogenous lev els of t he s mall f ragment of lamin a and lamin c res ult ing f rom c leav age at as part ic ac id 230. Mouse monoclonal 30h5 reactivity. The ant ibody does not c ros s reac t wit h f ull lengt h lamin a or c.

The antibody does not cross react with full length lamin a or c. Cleaved lamin a small subunit 30h5 mouse mab 2036 w if ic h m r lamin a c antibody 2032 w ip ihc p if ic f h m r b cleaved il 1b asp116 antibody 2021 w h il 1b antibody 2022 w h apoptosis lamin a a fodrin dff caspase 8 10 caspase 3 parp caspase 6 caspase 7 caspase 12 caspase si gnalin pathway tnf a death stimuli. Cleaved lamin a small subunit 30h5 mouse mab detects endogenous levels of the small fragment of lamin a and lamin c resulting from cleavage at aspartic acid 230. Also reacts with the larger fragments of lamin a 50 kda and lamin c 41 kda produced by caspase cleavage during apoptosis.

Cleaved lamin a small subunit 30h5 mouse mab detects endogenous levels of the small fragment of lamin a and lamin c resulting from cleavage at aspartic acid 230. Lamin a c is cleaved by caspase 6 and serves as a marker for caspase 6 activation.